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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1CC
All Species:
22.12
Human Site:
T311
Identified Species:
30.42
UniProt:
P36873
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36873
NP_002701.1
323
36984
T311
P
N
A
T
R
P
V
T
P
P
R
G
M
I
T
Chimpanzee
Pan troglodytes
XP_001144148
355
40088
T343
P
N
A
T
R
P
V
T
P
P
R
G
M
I
T
Rhesus Macaque
Macaca mulatta
XP_001108258
337
38500
T311
P
N
A
T
R
P
V
T
P
P
R
V
A
S
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P62137
330
37522
G311
G
K
Y
G
Q
F
S
G
L
N
P
G
G
R
P
Rat
Rattus norvegicus
P62138
330
37494
G311
G
K
Y
G
Q
F
S
G
L
N
P
G
G
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506012
354
40218
T342
P
N
A
S
R
P
V
T
P
P
R
G
M
I
T
Chicken
Gallus gallus
NP_001006190
323
36981
T311
P
N
A
S
R
P
V
T
P
P
R
S
M
I
T
Frog
Xenopus laevis
Q7SZ10
323
36919
T311
P
N
A
S
R
P
V
T
P
P
R
G
I
I
T
Zebra Danio
Brachydanio rerio
XP_700468
242
27469
F231
Q
G
T
N
V
S
R
F
T
V
T
A
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48461
327
37351
S309
F
V
Y
P
N
F
G
S
S
G
R
P
L
T
P
Honey Bee
Apis mellifera
XP_392943
329
37410
A311
L
T
Y
G
G
L
N
A
N
R
P
V
T
P
P
Nematode Worm
Caenorhab. elegans
P48727
333
37773
V310
Y
P
Y
G
A
G
G
V
G
S
N
R
P
V
T
Sea Urchin
Strong. purpuratus
XP_791029
330
37658
G311
K
F
P
Y
S
G
I
G
G
S
G
R
P
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
K294
M
C
S
F
Q
I
L
K
P
A
R
K
M
M
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48482
312
35513
I301
S
L
M
C
S
F
Q
I
L
K
P
A
D
R
K
Baker's Yeast
Sacchar. cerevisiae
P32598
312
35889
K296
L
C
S
F
Q
I
L
K
P
A
Q
K
S
L
P
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
K297
L
C
S
F
Q
I
L
K
P
A
E
K
K
Q
K
Conservation
Percent
Protein Identity:
100
90.9
94
N.A.
N.A.
91.8
92.1
N.A.
88.1
99
99
58.2
N.A.
88.6
91.4
89.4
88.4
Protein Similarity:
100
90.9
94.9
N.A.
N.A.
94.2
94.2
N.A.
89.5
99.6
100
61.2
N.A.
93.5
94.2
93.6
93.6
P-Site Identity:
100
100
73.3
N.A.
N.A.
6.6
6.6
N.A.
93.3
86.6
86.6
0
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
73.3
N.A.
N.A.
13.3
13.3
N.A.
100
93.3
100
0
N.A.
20
0
13.3
20
Percent
Protein Identity:
N.A.
73
N.A.
74.9
81.7
82.3
Protein Similarity:
N.A.
83.9
N.A.
84.2
89.4
89.7
P-Site Identity:
N.A.
20
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
46.6
N.A.
0
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
0
6
0
0
6
0
18
0
12
6
0
0
% A
% Cys:
0
18
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% E
% Phe:
6
6
0
18
0
24
0
6
0
0
0
0
0
0
0
% F
% Gly:
12
6
0
24
6
12
12
18
12
6
6
36
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
18
6
6
0
0
0
0
6
30
0
% I
% Lys:
6
12
0
0
0
0
0
18
0
6
0
18
6
0
12
% K
% Leu:
18
6
0
0
0
6
18
0
18
0
0
0
6
6
0
% L
% Met:
6
0
6
0
0
0
0
0
0
0
0
0
30
6
0
% M
% Asn:
0
36
0
6
6
0
6
0
6
12
6
0
0
0
0
% N
% Pro:
36
6
6
6
0
36
0
0
53
36
24
6
12
6
30
% P
% Gln:
6
0
0
0
30
0
6
0
0
0
6
0
0
6
0
% Q
% Arg:
0
0
0
0
36
0
6
0
0
6
48
12
0
18
0
% R
% Ser:
6
0
18
18
12
6
12
6
6
12
0
6
12
12
0
% S
% Thr:
0
6
6
18
0
0
0
36
6
0
6
0
6
6
42
% T
% Val:
0
6
0
0
6
0
36
6
0
6
0
12
0
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
30
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _